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马继登
作者: 发布日期:2020年04月24日 点击数:

姓名

马继登

政治面貌

中共党员

职称/职务

副教授

导师类型

硕导

联系电话

17780516256

电子邮箱

jideng.ma@sicau.edu.cn

研究方向

猪遗传育种与功能基因组学

学术、技术组织任职/头衔

中国畜牧兽医学会动物遗传育种学分会会员、四川省实验动物学会非人灵长类实验动物专委会委员、四川省畜牧兽医学会养猪学分会会员、四川省科技青年联合会会员、四川省生物信息学学会会员

受教育及

工作经历

教育经历:

1.2011-09至2014-06,四川农业大学,金沙贵宾厅-优惠大厅,博士

2.2009-09至2011-06,四川农业大学,金沙贵宾厅-优惠大厅,硕士

3.2005-09至2011-06,四川农业大学,金沙贵宾厅-优惠大厅,学士

工作经历:

1.2020-04至今,四川农业大学,动物遗传育种研究所,副所长

2.2018-12至今,四川农业大学,动物遗传育种研究所,副教授

3.2016-09至2020-04,四川农业大学,动物遗传育种研究所,猪研究室主任

4.2014-06至2018-12,四川农业大学,动物遗传育种研究所,讲师

教学课程

硕士生《猪遗传育种与繁殖研究进展》、《牧场经营与管理》和本科生《生物统计实验》

人才培养情况

培养硕士研究生3人,在读硕士研究生5人;协助培养硕士研究生30余人,博士研究生9人

科研项目

(近五年)

1.国家科学技术部,国家重点研发计划项目,2018YFD0501204,特色地方猪高效安全养殖技术应用与示范,2018-06至2020-12,在研,参与

2.国家自然科学基金委员会,青年科学基金项目, 31601918,猪高原低氧获得性习服相关的DNA甲基化组变异及其跨代遗传的表观调控, 2017-01至2019-12,已结题,主持

3.国家自然科学基金委员会,重点项目,31530073,猪骨骼肌生长和脂肪发育及分布相关功能基因和调控元件的筛选、鉴定和育种价值评估,2016-01至2020-12,在研,参与

4.国家自然科学基金面上项目,31472081,猪体内食物源性植物microRNA对内源靶mRNA基因的调控,2015-01至2018-12,已结题,参与

代表性论文

近年来在猪重要经济性状的功能基因组学领域做了大量研究工作,发表SCI论文51篇,累计影响因子超过200。其中,以第一(共同第一)或通讯作者在Scientific Data、Frontiers In Genetics、International Journal of Molecular Sciences、PloS One等杂志发表SCI论文20余篇。作为“猪分子遗传育种”四川省青年科技创新研究团队的研究骨干,在团队带头人李明洲教授的带领下先后于2012、2013和2016年在Nature Communications、Nature Genetics和 Genome Research杂志发表了以猪为研究对象的代表性论文:

(1) Keren Long#, Siyuan Feng#,Jideng Ma#, Jinwei Zhang, Long Jin, Qianzi Tang, Xun Wang, Miaomiao Mai, Weihang Xiao, Lingyan Liu, Xuewei Li, Mingzhou Li*, Small non-coding RNA transcriptome of four high-altitude vertebrates and their low-altitude relatives, Scientific Data, 2019, 6: 0-192

(2) Can Liu#,Jideng Ma#, Jinwei Zhang#, Han Zhao, Yan Zhu, Jing Qi, Lingyan Liu, Li Zhu, Yanzhi Jiang, Guoqing Tang, Xuewei Li, Mingzhou Li*, Testosterone Deficiency Caused by Castration Modulates Mitochondria Biogenesis Through the AR/PGC1 alpha/TFAM Pathway, Frontiers in Genetics, 2019, 10: 0-505

(3) Jinwei Zhang#, Wanling Qiu#,Jideng Ma#, Yujie Wang, Zihui Hu, Keren Long, Xun Wang, Long Jin, Qianzi Tang, Guoqing Tang, Li Zhu, Xuewei Li, Surong Shuai* and Mingzhou Li*, International Journal of Molecular Sciences, 2019, 20 (10): 2418

(4) Jideng Ma#, Yu Fan#, Jinwei Zhang#, Siyuan Feng, Zihui Hu, Wanling Qiu, Keren Long, Long Jin, Qianzi Tang, Xun Wang, Qi Zhou, Yiren Gu, Weihang Xiao, Lingyan Liu, Xuewei Li*, Mingzhou Li*, Testosterone-Dependent miR-26a-5p and let-7g-5p Act as Signaling Mediators to Regulate Sperm Apoptosis via Targeting PTEN and PMAIP1, International Journal of Molecular Sciences, 2018, 19 (4) :1233

(5) Jideng Ma#, Jinwei Zhang#, Yujie Wang# , Keren Long , Xun Wang, Long Jin, Qianzi Tang, Li Zhu, Guoqing Tang, Xuewei Li, Mingzhou Li*, MiR-532-5p alleviates hypoxia-induced cardiomyocyte apoptosis by targeting PDCD4, Gene, 2018, 675:36-43

(6) Yujie Wang#,Jideng Ma#, Wanling Qiu#, Jinwei Zhang, Siyuan Feng, Xiankun Zhou, Xun Wang, Long Jin, Keren LongOrcID, Lingyan Liu, Weihang Xiao, Qianzi Tang, Li Zhu, Yanzhi Jiang, Xuewei Li*, Mingzhou Li*, Guanidinoacetic Acid Regulates Myogenic Differentiation and Muscle Growth Through miR-133a-3p and miR-1a-3p Co-mediated Akt/mTOR/S6K Signaling Pathway, International Journal of Molecular Sciences, 2018,19:2837-2855

(7) Jideng Ma#, Chengdong Wang#, Keren Long#, Hemin Zhang#*, Jinwei Zhang, Long Jin, Qianzi Tang, Anan Jiang, Xun Wang, Shilin Tian, Li Chen, Dafang He, Desheng Li, Shan Huang, Zhi Jiang*, Mingzhou Li*, Exosomal microRNAs in giant panda (Ailuropoda melanoleuca) breast milk: potential maternal regulators for the development of newborn cubs, Scientific Reports, 2017, 7: 3507

(8) Jinwei Zhang#,Jideng Ma#, Keren Long#, Wanling Qiu, Yujie Wang, Zihui Hu, Can Liu, Yi Luo, Anan Jiang, Long Jin, Qianzi Tang, Xun Wang, Xuewei Li*,Mingzhou Li*, Overexpression of Exosomal Cardioprotective miRNAs Mitigates Hypoxia-Induced H9c2 Cells Apoptosis, International Journal of Molecular Sciences, 2017, 18(4):711-725

(9) Dafang He#,Jideng Ma#, Keren Long#, Xun Wang, Xuewei Li, Anan Jiang*, Mingzhou Li*, Differential expression of genes related to glucose metabolism in domesticated pigs and wild boar, Bioscience Biotechnology & Biochemistry, 2017, 81(8):1

(10) Jiuqiang Guan#, Keren Long#,Jideng Ma#, Jinwei Zhang, Dafang He, Long Jin, Qianzi Tang, Anan Jiang, Xun Wang, Yaodong Hu, Shilin Tian, Zhi Jiang, Mingzhou Li*, Xiaolin Luo*, Comparative analysis of the microRNA transcriptome between yak and cattle provides insight into high-altitude adaptation, Peerj, 2017, 5(25):e3959

(11) Hongmei Wang#,Jideng Ma#, Long Jin, Yihui Liu, Tiandong Che, Mingzhou Li*, Xuewei Li*, Developmental methylation pattern regulates porcine GPR120 expression, Genetics and Molecular Research, 2016, 15(1): gmr.15014240

(12) Jie Zhang#,Jideng Ma#, Keren Long#, Long Jin, Yihui Liu, Chaowei Zhou, Shilin Tian, Lei Chen, Zonggang Luo, Qianzi Tang, An’an Jiang, Xun Wang, Dawei Wang, Zhi Jiang, Jinyong Wang, Xuewei Li*, Mingzhou Li*, Dynamic gene expression profiles during postnatal development of porcine subcutaneous adipose, Peerj, 2016, 4(2):e1768

(13) Jideng Ma#, Hongmei Wang#, Rui Liu,Long Jin,Qianzi Tang,Xun Wang,Anan Jiang,Yaodong Hu,Zongwen Li, Li Zhu, Ruiqiang Li, Mingzhou Li*, Xuewei Li*, The miRNA Transcriptome Directly Reflects the Physiological and Biochemical Differences between Red, White, and Intermediate Muscle Fiber Types, International Journal of Molecular Sciences, 2015, 16: 9635-9653

(14) Keren Long#,Jideng Ma#, Li Chen, Pengjun Wang, Dafang He, Mingzhou Li*, Xuewei Li*, Promoter and first exon methylation regulate porcine FASN gene expression, GeneGenetics and Molecular Research, 2015, 14(3): 8443-8450

(15) Jideng Ma#, Shuzhen Yu#, Fengjiao Wang, Lin Bai, Jian Xiao, Yanzhi Jiang, Lei Chen, Jinyong Wang, Anan Jiang, Mingzhou Li*, Xuewei Li*, MicroRNA Transcriptomes Relate Intermuscular Adipose Tissue to Metabolic Risk, International Journal of Molecular Sciences, 2013, 14(4): 8611-8624

(16) Jideng Ma#, Zhi Jiang#, Shen He#, Yingkai Liu, Lei Chen, Keren Long, Long Jin, An'an Jiang, Li Zhu, Jinyong Wang, Mingzhou Li*, Xuewei Li*, Intrinsic features in microRNA transcriptomes link porcine visceral rather than subcutaneous adipose tissues to metabolic risk, PLos One, 2013, 8(11): e80041-e80041

(17) Jideng Ma#, Mingzhou Li, Shulin Zhou, Caowei Zhou, Xuewei Li*, Methylation-sensitive amplification polymorphism analysis of fat and muscle tissues in pigs, Genetics and Molecular Research, 2012, 11(3): 3505-3510

(18) Jideng Ma#, Mingzhou Li, Huiyu Wang, Xuewei Li*, Genotyping of the porcine ryanodine receptor 1 (RYR1) and estrogen receptor 1 (ESR1) genes by high resolution melting (HRM) approach, Biotechnology and Bioprocess Engineering, 2012, 17(15): 1076-1079

(19) Yingkai Liu#, Mingzhou Li#, JidengMa, Jie Zhang, Chaowei Zhou, Tao Wang, Xiaolian Gao, Xuewei Li*, Identification of differences in microRNA transcriptomes between porcine oxidative and glycolytic skeletal muscles, BMC Molecular Biology, 2013, 14: 7-7

(20) Mingzhou Li#, Shilin Tian#, Long Jin#, Guangyu Zhou#, Ying Li#, Yuan Zhang, Tao Wang, Carol K L Yeung, Lei Chen,Jideng Ma, Jinbo Zhang, Anan Jiang, Ji Li, Chaowei Zhou, Jie Zhang, Yingkai Liu, Xiaoqing Sun, Hongwei Zhao, Zexiong Niu, Pinger Lou, Lingjin Xian, Xiaoyong Shen, Shaoqing Liu, Shunhua Zhang, Mingwang Zhang, Li Zhu, Surong Shuai, Lin Bai, Guoqing Tang, Haifeng Liu, Yanzhi Jiang, Miaomiao Mai, Jian Xiao, Xun Wang, Qi Zhou, Zhiquan Wang, Paul Stothard, Ming Xue, Xiaolian Gao, Zonggang Luo, Yiren Gu, Hongmei Zhu, Xiaoxiang Hu, Yaofeng Zhao, Graham S Plastow, Jinyong Wang, Zhi Jiang, Kui Li, Ning Li, Xuewei Li*, Ruiqiang Li*, Genomic analyses identify distinct patterns of selection in domesticated pigs and Tibetan wild boars, Nature Genetics, 2013, 45(12): 1431-1438

(21) Li, Mingzhou#, Wu, Honglong#, Luo, Zonggang, Xia, Yudong, Guan, Jiuqiang, Wang, Tao, Gu, Yiren, Chen, Lei, Zhang, Kai,Ma, Jideng, Liu, Yingkai, Zhong, Zhijun, Nie, Jing, Zhou, Shuling, Mu, Zhiping, Wang, Xiaoyan, Qu, Jingjing, Jing, Long, Wang, Huiyu, Huang, Shujia, Yi, Na, Wang, Zhe, Xi, Dongxing, Wang, Juan, Yin, Guangliang, Wang, Li, Li, Ning, Jiang, Zhi, Lang, Qiulei, Xiao, Huasheng, Jiang, Anan, Zhu, Li, Jiang, Yanzhi, Tang, Guoqing, Mai, Miaomiao, Shuai, Surong, Li, Ning, Li, Kui, Wang, Jinyong, Zhang, Xiuqing, Li, Yingrui, Chen, Haosi, Gao, Xiaolian, Plastow, Graham S, Beck, Stephen, Yang, Huanming, Wang, Jian, Wang, Jun, Li, Xuewei*, Li, Ruiqiang*, An atlas of DNA methylomes in porcine adipose and muscle tissues, Nature Communications, 2012, 3: 850-850

(22) Mingzhou Li#, Yingkai Liu#, Tao Wang, Jiuqiang Guan, Zonggang Luo, Haosi Chen, Xin Wang, Lei Chen,Jideng Ma, Zhiping Mu, Anan Jiang, Li Zhu, Qiulei Lang, Xiaochuan Zhou, Jinyong Wang, Wenxian Zeng, Ning Li, Kui Li, Xiaolian Gao, Xuewei Li*, Repertoire of porcine microRNAs in adult ovary and testis by deep sequencing, International Journal of Biological Sciences, 2012, 7(7): 1045-1055

(23) Mingzhou Li#, Lei Chen#, Shilin Tian#, Yu Lin#, Qianzi Tang#, Xuming Zhou#, Diyan Li, Carol KL Yeung, Tiandong Che, Long Jin, Yuhua Fu,Jideng Ma, Xun Wang, Anan Jiang, Jing Lan, Qi Pan, Yingkai Liu, Zonggang Luo, Zongyi Guo, Haifeng Liu, Li Zhu, Surong Shuai, Guoqing Tang, Jiugang Zhao, Yanzhi Jiang, Lin Bai, Shunhua Zhang, Miaomiao Mai, Changchun Li, Dawei Wang, Yiren Gu, Guosong Wang, Hongfeng Lu, Yan Li, Haihao Zhu, Zongwen Li, Ming Li, Vadim N. Gladyshev, Zhi Jiang, Shuhong Zhao, Jinyong Wang, Ruiqiang Li, and Xuewei Li, Comprehensive Variation Discovery and Recovery of Missing Sequence in the Pig Genome using Multiple De Novo Assemblies, Genome Research, 2017. 27: 865-874

各类获奖


专利、新品种、教材、专著等

专利:

1.一种从动物血浆中分离外泌体并进行纯度检测的方法2020.02, 发明专利,排名2

2.猪雌激素受体基因快速分型试剂盒及其检测方法, 2013.11,发明专利,排名1

3.猪氟烷基因快速分型试剂盒及其检测方法, 2013.12, 发明专利,排名1

4.一种新型临产母猪全身清洗装置、猪舍, 2018.08, 实用新型专利,排名3

5.一种动物胴体分割称量装置, 2018.06,实用新型专利,排名2

6.一种新型早期哺乳仔猪饲喂槽、猪舍, 2018.04, 实用新型专利,排名3

7.一种野外全血静置的保温装置, 2017.12,实用新型专利,排名2

8.一种新型教槽料饲喂槽, 2017.07,实用新型专利,排名3

9.肉猪养殖环境监测系统V1.0, 2018-08-17, 排名1

10.养殖肉猪技术培训系统V1.0, 2018-08-16, 排名1

11.肉猪养殖场温度监控系统V1.0, 2018-08-16, 排名1

12. 肉猪养殖场管理系统V1.0, 2018-08-16,排名1

13.肉猪养殖场热回收动态控制系统V1.0, 2018-08-15,排名1

成果鉴定:

1.“高繁美系种猪选育研究与应用”(2017,第9位)

2.“四川省种猪遗传改良体系建立和配套系选育研究与应用”(2013,第14位)

社会服务

积极投身生猪产业发展和脱贫攻坚,协助各级地方政府编制生猪产业发展规划7套;积极配合各级政府和企业生猪产业发展需要,组织培训生猪一线技术人员1000余人次;针对产业需求,长期协助省内外生猪养殖企业实行技术攻关、育种公关、产业链技术集成与示范等事务